Publications
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The American journal of physiology
1989
Proceedings of the National Academy of Sciences of the United States of America
1989
Biochimica et biophysica acta
1989
Journal of cellular physiology
1989
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
1989
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
1989
Biochimica et biophysica acta | Volume 991 of Issue 3
1989
We report the ability of focused soft X-rays to visualize at spatial resolution well beyond that of the optical microscope (less than 100 nm) the interior of a small, whole biological object without fixation, staining, dehydration or sectioning. Quantitative estimation of its protein content with unique femtogram sensitivity is also reported. The present results represent a significant step towards the goals of natural imaging and chemical mapping of biological structures with soft X-rays.
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