Oncology (Williston Park, N.Y.) | Volume 31 of Issue 11
Authors: Ursem C, Venook AP
The first studies of epidermal growth factor receptor (EGFR) inhibitors in metastatic colorectal cancer were begun before the predictive role of RAS mutations had been elucidated. Secondary analyses of many large randomized trials have shown that mutations in exons 2-4 of KRAS and NRAS, BRAF V600E mutation, and right-sided primary tumor all predict lack of response to EGFR inhibition in the first-line setting. However, even in patient populations defined by a lack of these negative predictors, there is still not uniform response to anti-EGFR therapy. Additionally, although older adults have been shown to have the potential to both tolerate and respond to anti-EGFR therapy, the criteria for selecting the most appropriate older patients for treatment remain unclear.
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Surgical endoscopy | Volume 32 of Issue 1
Authors: Ryou M, McQuaid KR, Thompson CC, Edmundowicz S, Mergener K,
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract | Volume 22 of Issue 2
Authors: Ryou M, McQuaid KR, Thompson CC, Edmundowic S, Mergener K
Journal of the American Heart Association
Authors: Huang C, Dhruva SS, Coppi AC, Warner F, Li SX, Lin H, Nasir K, Krumholz HM
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Authors: Collins SP, Levy PD, Fermann GJ, Givertz MM, Martindale JM, Pang PS, Storrow AB, Diercks DD, Michael Felker G, Fonarow GC, Lanfear DJ, Lenihan DJ, Lindenfeld JM, Frank Peacock W, Sawyer DM, Teerlink JR, Butler J
The New England journal of medicine
Authors: Weisbord SD, Gallagher M, Jneid H, Garcia S, Cass A, Thwin SS, Conner TA, Chertow GM, Bhatt DL, Shunk K, Parikh CR, McFalls EO, Brophy M, Ferguson R, Wu H, Androsenko M, Myles J, Kaufman J, Palevsky PM
Journal of surgical oncology
Authors: Onega T, Weiss JE, Goodrich ME, Zhu W, DeMartini WB, Kerlikowske K, Ozanne E, Tosteson ANA, Henderson LM, Buist DSM, Wernli KJ, Herschorn SD, Hotaling E, O'Donoghue C, Hubbard R
Journal of the American Geriatrics Society
Authors: Wu C, Peralta CA, Odden MC
Gastrointestinal endoscopy
Authors: Abbas AM, Strong AT, Diehl DL, Brauer BC, Lee IH, Burbridge R, Zivny J, Higa JT, Falcão M, El Hajj II, Tarnasky P, Enestvedt BK, Ende AR, Thaker AM, Pawa R, Jamidar P, Sampath K, Hourneaux de Moura EG, Kwon RS, Suarez AL, Aburajab M, Wang AY, Shakhatreh MH, Kaul V, Kang L, Kowalski TE, Pannala R, Tokar J, Aadam AA, Tzimas D, Wagh MS, Draganov PV
The American journal of gastroenterology | Volume 113 of Issue 3
Authors: Grimm I, Peery AF, Kaltenbach T, Crockett SD
