Circulation
Authors: Monik C Jimenez, Lenny Lopez, Kathryn M Rexrode
Circulation
Authors: Alexandra K Lee, Ronit Katz, Walter T Ambrosius, Alfred K Cheung, Pranav Garimella, Lisa H Gren, Vasantha Jotwani, Javier A Neyra, Henry Punzi, Kalani Raphael, Joachim H Ix, Michael Shlipak
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Authors: Yu JX, Russell WA, Ching JH, Kim N, Bendavid E, Owens DK, Kaltenbach T
Menopause (New York, N.Y.)
Authors: Gibson CJ, Li Y, Bertenthal D, Huang AJ, Seal KH
Cell & bioscience
Authors: Kido T, Lau YC
Gastrointestinal endoscopy
Authors: Patel SG, Duloy A, Kaltenbach T, Hall M, Kahi C, Pohl H, Rastogi A, Hammad H, Soetikno R, Shergill A, Simon V, Nguyen T, Ezekwe E, Ahi T, Keswani RN, Wani S
JAMA network open
Authors: Norgeot B, Glicksberg BS, Trupin L, Lituiev D, Gianfrancesco M, Oskotsky B, Schmajuk G, Yazdany J, Butte AJ
AIDS (London, England)
Authors: Turan B, Rice WS, Crockett KB, Johnson M, Neilands TB, Ross SN, Kempf MC, Konkle-Parker D, Wingood G, Tien PC, Cohen M, Wilson TE, Logie CH, Sosanya O, Plankey M, Golub E, Adimora AA, Parish C, Weiser SD, Turan JM
Emerging infectious diseases | Volume 25 of Issue 3
Authors: Osman M, Harausz EP, Garcia-Prats AJ, Schaaf HS, Moore BK, Hicks RM, Achar J, Amanullah F, Barry P, Becerra M, Chiotan DI, Drobac PC, Flood J, Furin J, Gegia M, Isaakidis P, Mariandyshev A, Ozere I, Shah NS, Skrahina A, Yablokova E, Seddon JA, Hesseling AC, Collaborative Group for Meta-Analysis of Paediatric Individual Patient Data in MDR TB
Extensively drug-resistant tuberculosis (XDR TB) has extremely poor treatment outcomes in adults. Limited data are available for children. We report on clinical manifestations, treatment, and outcomes for 37 children (<15 years of age) with bacteriologically confirmed XDR TB in 11 countries. These patients were managed during 1999-2013. For the 37 children, median age was 11 years, 32 (87%) had pulmonary TB, and 29 had a recorded HIV status; 7 (24%) were infected with HIV. Median treatment duration was 7.0 months for the intensive phase and 12.2 months for the continuation phase. Thirty (81%) children had favorable treatment outcomes. Four (11%) died, 1 (3%) failed treatment, and 2 (5%) did not complete treatment. We found a high proportion of favorable treatment outcomes among children, with mortality rates markedly lower than for adults. Regimens and duration of treatment varied considerably. Evaluation of new regimens in children is required.
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AIDS (London, England)
Authors: Sharma A, Shi Q, Hoover DR, Tien PC, Plankey MW, Cohen MH, Golub ET, Gustafson D, Yin MT