Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Authors: Le V, Pascopella L, Westenhouse J, Barry P
BACKGROUND
Recognizing pulmonary involvement in tuberculosis (TB) patients is necessary to prevent TB transmission. We describe frequency and characteristics of patients with extrapulmonary TB (EPTB), normal chest radiographs, and positive sputum culture.
METHODS
We analyzed data on patients ≥15 years old with EPTB reported to the California TB registry during 2011-2017 with cultured sputum and normal chest radiographs, using generalized linear modeling to estimate prevalence ratios associated with positive sputum culture. Demographic, behavioral, clinical characteristics, and testing were compared for patients with positive and negative sputum culture.
RESULTS
Of 1,634 patients with EPTB and normal chest radiographs, 936 (57%) had sputum culture performed, and 126 (13%) patients had positive results for M. tuberculosis complex. Patients with positive results were more likely to: be male, experience homelessness, use substances, have HIV, have >1 disease site. Among 85 HIV co-infected patients, 54% had positive culture results compared to 9.5% among 852 patients without HIV co-infection. Patients with EPTB in more than one site were also more likely to have a positive sputum culture.
CONCLUSIONS
Culturing sputum from patients with EPTB identified pulmonary cases not detected by chest radiograph, particularly among patients with HIV or >1 disease site.
View on PubMed
"HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support"
Authors: Bikle DD
TO REMOVE
Authors: Price JC, Ma Y, Kuniholm MH, Adimora AA, Fischl M, French AL, Golub ET, Konkle-Parker D, Minkoff H, Ofotokun I, Plankey M, Sharma A, Tien PC
Psychiatric services (Washington, D.C.)
Authors: Timko C, Hoggatt KJ, Esmaeili A, Lewis E, Lor MC, Maust DT, Nevedal AL
Neurology
Authors: Meghan Pawlik, Maryam Zafar, Samantha Lettenberger, Madeleine Coffey, Aayush Sarkar, Caroline Tanner, Samuel Goldman, Briana De Miranda, Karl Kieburtz, Daniel Kinel, E. Ray Dorsey
Neurology
Authors: Nijee Luthra, Ethan Brown, Samuel Goldman, Rafael Zuzuarregui, Trisha Hue, Christopher Schambach, Ian Bledsoe, Michael Schwarzschild, E. Ray Dorsey, Alberto Espay, Irene Litvan, Nikolaus McFarland, Kyle Mitchell, David Standaert, James Beck, Helen Rowbotham, Cheryl Meng, Jacque Perkins, Primi Ranola, Raymundo Picos, Dana Kriesel, Kenneth Lyles, Steve Cummings, Caroline Tanner
Journal of general internal medicine
Authors: Wray CM, Sridhar A, Young A, Noyes C, Smith WB, Keyhani S
TO REMOVE
Authors: Shlipak MG, Sheshadri A, Hsu FC, Chen SH, Jotwani V, Tranah G, Fielding RA, Liu CK, Ix J, Coca SG, LIFE Investigators
"HIV within the House Ball Community and the Promise of Community-based Social Structures for Intervention and Support"
Authors: Kwan A, Sears D, Bertozzi SM, Williams B, editors.
Gastroenterology
Authors: Parakkal Deepak, Wooseob Kim, Michael Paley, Monica Yang, Samantha Burdess, Alexander B. Carvidi, Emanuel Demissie, Alia A. El-Qunni, Alem Haile, Katherine Huang, Guadalupe Oliva Escudero, Lily E. McMorrow, Diana Paez, Niti Pawar, Dana C. Perantie, Rebecca E. Schriefer, Shannon E. Sides, Mahima Thapa, Maté Gergely, Sewuese E. Akuse, Michael Klebert, Lynne Mitchell, Billy D. Nix, Jonathan Graf, Kimberly E. Taylor, Salim Chahin, Matthew A. Ciorba, Patricia Katz, Mehrdad Matloubian, Jane A. O'Halloran, Rachel M. Presti, Gregory F. Wu, Lianne S. Gensler, Mary C. Nakamura, Ali H. Ellebedy, Alfred H. Kim